quit success (Uhl et al., 2010a). The use of a genome-wide derived polygenic scores is consistent with the belief that complex human behavior is likely a product of a multiple genes working in concert (Duncan et al. 2014; Plomin et al., 2009) as illustrated in Musci et al. (2015a), wherein a polygenic score was used to predict the course of internalizing symptoms across the adolescence along with early environmental risk.