Similar studies in rhesus macaques showed that carriers of the 77G variant that is functionally equivalent to the human 118G (see animal models of 118A>G, above) were selectively sensitive to suppression of alcohol preference by NTX treatment (Barr et al. 2010), were more sensitive to the effects of NTX, and showed greater reductions in alcohol consumption at lower NTX doses (Vallender et al. 2010).
