Chunk #12 — METHODS AND MATERIALS — Estimation of future risk gene discovery

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De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette's Disorder and Autism.

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Based on the predicted number of OCD risk genes, we performed simulations to predict the likely future gene discovery yield as additional OCD trios are investigated by WES. See Supplemental Methods for details of these calculations.