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Chunk #16 — RESULTS — Association Between GABRA2 and Acute Adaptation

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Role of GABRA2 in moderating subjective responses to alcohol.
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All but the SNP6 had no significant association with acute adaptation (data not shown). In the GABRA2 SNP6, subjects with ALDH2*1/*1 showed significant association with acute adaptation in Dynamic Peripheral [F (2, 72) = 6.39, p = 0.003] subscale of SS and Stimulant [F (2, 70) = 4.01, p = 0.023] and Sedative [F (2, 69) = 5.49, p = 0.006] subscales of BAES. By contrast, there were no significant effects of the SNP6 on the acute adaptation in those with ALDH2*1/*2. Significant levels of all these results are shown in Table 3.