Genome-wide significant loci for BD were assessed for overlap with genome-wide significant loci for other psychiatric disorders, using the largest available GWAS results for major depression61, schizophrenia60, attention deficit/hyperactivity disorder101, post-traumatic stress disorder102, lifetime anxiety disorder103, Tourette’s Syndrome104, anorexia nervosa105, alcohol use disorder or problematic alcohol use68, autism spectrum disorder106, mood disorders91 and the cross-disorder GWAS of the Psychiatric Genomics Consortium66. The boundaries of the genome-wide significant loci were calculated in the original publications. Overlap of loci was calculated using bedtools v2.29.2107.