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Chunk #34 — Results — Statistical Analyses — Target sources

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Novelty P3 reductions in depression: characterization using principal components analysis (PCA) of current source density (CSD) waveforms.
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Significant ANOVA results for target and novel stimuli are shown in Table 3 for factors 241, 343, and 542. Evidence suggesting midparietal source reduction and midfrontal P3 source enhancement for 343 in patients (cf. Figure 5, column 2) was not preserved when age was included as a covariate. A notable P3b asymmetry at lateral temporoparietal sites was also unrelated to group. However, the midfrontal response-related sink (542) was significantly reduced in patients, the corresponding centroparietal source being reduced at sites CP1/2, and larger over the left than right hemisphere.