Pedigrees were derived from the 580 tribal members recruited in phase 1 and the 117 additional participants recruited in phase 3. Pedigrees were constructed through a lengthy process of consultation and discussion with senior tribal members. In addition, the DNA samples of phase 3 participants were genotyped for 10 short tandem repeat markers to correct for Mendelian inconsistencies. PedCheck [54] was used as a second check for Mendelian inconsistent genotyping data. Most tribal members belonged to one large pedigree (n = 1004). In addition 101 tribal members were distributed in five other pedigrees (n = 14–33).
