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Chunk #53 — Materials and Methods — There were three phases to this study — Pedigree structure

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Common genetic origins for EEG, alcoholism and anxiety: the role of CRH-BP.
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DNA was available for 353 Plains Indians. Six individuals who were misgendered/mixed identity were excluded. Nineteen samples failed to genotype. Therefore data from 328 DNAs were used in the transmission and linkage analyses after confirmation. Genotypes plus EEG data were available for 266 Plains Indians: 249 from the one large pedigree and 17 from the 5 small pedigrees (2–5 per pedigree).