Chunk #17 — MATERIALS AND METHODS — Statistical model — QuantiSNP: an Objective Bayes Hidden-Markov Model — Objective learning, expectation maximization(EM) and the Viterbi algorithm

Source

QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data.

Embedded

yes

Text

The Viterbi algorithm can then be used to compute the sequence of hidden states with highest probability given the MAP parameter estimates of the emission model parameters and hyperparameter, 11