levels56. A subset of the genes in this region (e.g. IP6K1, CAMKV, SEMA3F) have been associated with educational attainment57.Region B350.264–53.080 MbWorry itemsGenes in this region (e.g. ALAS1, STAB1, GNL3, ITIH4, TMEM110) have been linked to schizophrenia and autism spectrum disorder in earlier studies58,59.All genes that were GWS in gene-based analyses in MAGMA23 on all 13 neuroticism phenotypes are reported in Supplementary Data 33.CHR: Chromosome on which the gene is located.Position: Start position of the gene in base pairs (for the regions A and B a start and end position is reported).Depressed affect and worry refer to two separate sets of 4 items each, i.e., LONE/MIS/MOOD/FED-UP, and NERV-FEEL/WORRY/TENSE/SUF-NERV, respectively.See Supplementary Table 1 for a description of the item labels.
