We estimated the SNP-heritability of AUDIT total score to be 12% (GCTA: ± 0.48%, p = 4.6 × 10−273; LDSC: 8.6% ± 0.50%), which is similar to the estimate from Sanchez-Roige et al. (10). The SNP-heritability for AUDIT-C was 11% (GCTA: ±0.47%, p = 1.5 × 10−211; LDSC: 8.4% ±0.55%), and 9% for AUDIT-P (GCTA: ±0.46%, p = 2.0 × 10−178; LDSC: 5.9% ±0.48%).