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Chunk #14 — Methods — Polygenic Score (PGS) Calculation — Statistical Framework

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The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study.
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We utilized nonmelanoma skin cancer (NMSC) as a comparator, as NMSC does not appear to be associated with psychotic disorders.44 Meanwhile, we carried out sensitivity analyses leveraging 1031 participants without recent cannabis use in the past 2 years (Supplementary Methods).