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Chunk #15 — Results — Genetic Architecture of Psychotic Disorders and Cannabis Phenotypes

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The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study.
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Estimated heritability (range=7–38%) was greater among psychotic disorders than among cannabis phenotypes while, polygenicity was lowest for CUD (3.7k trait-influencing variants; Figure 1, Supplementary Table 2, and Supplementary Figure 2). Meanwhile, LCU was 75% genetically less discoverable than other phenotypes.