Data from all offspring SSAGA and cSSAGA interviews were used to obtain lifetime reports of alcohol and cannabis use as previously detailed.56,59 Participants’ AUD symptom count scores and CUD symptom count scores were based on DSM-5 lifetime symptom counts. INT psychopathology count scores included DSM-IV lifetime diagnoses for major depressive disorder, panic disorder, social phobia, and an additional item—suicidal ideation. EXT psychopathology count scores included conduct disorder and oppositional defiant disorder diagnoses. Data from each individual’s most recent interview were used.