agrees with previous studies showing that the expression of the GR exon 17 splice variant as well as that of exon 2 is increased in High LG offspring ([6], [7]; Fig. 4b ). Furthermore, we also detected increased transcription among High LG offspring in each of the exon 1 splice variants known to be expressed in the hippocampus: GR15, GR16, GR17, GR110, and GR111 ([30]; Fig. 4b ). These results suggest that broad epigenetic differences within the NR3C1 gene as well as the coordinated expression pattern of NR3C1 splice variants may be involved in the response to maternal care.
