The most common reconstructed haplotype extended across all 15 SNPs in EAs (haplotype frequency 15%) and the second most common in AAs (haplotype frequency 4%) includes the derived rs4680 Met allele but also the derived alleles at three other SNPs (rs933271, rs5993883, and rs740603). The most common 15-SNP reconstructed haplotype in AAs (haplotype frequency 6%) contains the four ancestral alleles at the same loci. In EAs, this haplotype (i.e., the most common AA haplotype) has a frequency of 3%.
