Figure 2 shows the regional association plots for three independent signals near rs4424567 at FRMD4A, rs848353 at 7q31.1, and rs2349433 (rs7747583) at RGS17. We found that two SNPs, rs7747583 and rs2349433 at RGS17, are in complete LD, with r2 = 0.99. The regional association plots using both genotypes and imputed SNPs support our findings. As shown in Fig. 2a, SNP rs4424567 hovers in the intronic region of FRMD4A. Figure 2b shows that SNP rs848353 is part of a large cluster of associated SNPs near C7orf66. Figure 2c shows the dense cluster of associated SNPs, including the lead SNP rs2349433, in RGS17.
