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Chunk #25 — Results — Associations of CD with the positive variants identified in the EA family sample in the other three independent samples

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Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.
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The above EA family-based association tests suggested that SNP8 and the interaction between SNP8 and SNP3 were associated with risk for CD. We replicated these positive associations using the other three independent samples, i.e., an EA case-control sample, an AA case-control sample and an AA family sample.