Chunk #141 — IV. Results of tests of clustering within individual samples and tests of convergence between replicate samples for the same phenotypes — C. Bipolar disorder vs control (Samples 7, 8 and 9)
Convergent data from at least two of the three bipolar vs control comparisons: Simluation trials assessed the likelihood that the clusters of nominally-positive SNPs from at least two of these three bipolar samples identified the same genes. Monte Carlo simulation trials that assessed the probabilities that these results were due to chance found that none of 100,000 simulation trials identified as many clustered SNPs that displayed nominally-positive differences between bipolar vs control samples in the same genes in multiple samples as we actually observe (thus p < 0.00001).
