Chunk #142 — IV. Results of tests of clustering within individual samples and tests of convergence between replicate samples for the same phenotypes — D. Frontal brain volume (Samples 10 and 11)
10,266 SNPs provide nominally-positive results in 500k Affymetrix data from unrelated members of NHLBI twin pairs (Uhl et al, submitted). 583 of these 10,266 nominally-positive SNPs fall into 169 chromosomal clusters that each contain at least three nominally-positive SNPs that lie within 25 kb of each other and come from both the Sty I and Nsp I array types. Monte Carlo trials did not identify such a degree of clustering in any of 100,000 simulation trials (thus p < 0.00001).
