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Chunk #18 — Results — Association with Previously Reported Schizophrenia Loci — GWAS

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A genome-wide investigation of SNPs and CNVs in schizophrenia.
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We then went on to check the p values for the following SNPs, or their closest proxy within 100 kb that was genotyped in our schizophrenia samples: the top 63 SNPs shown to be associated with individual genotyping in Kirov et al [19], the top 25 SNPs from Sullivan et al [14] and all individually genotyped SNPs that had a p<0.05 in combined males and females from Shifman et al [18]. These particular SNPs were chosen because only these p values were made publically available in the papers. Of these 116 SNPs, 8 were not represented in our dataset. Of the other 108, 6 were associated at p<0.05, and the lowest p value was 0.002 for rs11595716, a proxy for rs17746501, associated in Shifman et al. at p = 0.007 [18](see Table S2 for all data). This SNP is not located in a gene, nor is it strongly associated with any other SNP in or close to a gene. The other associated SNPs had p values of 0.011 (proxy for rs151222), 0.015 (proxy for rs234993), 0.020 (proxy for rs208799), 0.044