The expression data of 14,925 transcripts in 93 autopsy-collected frontal cortical brain tissue samples were evaluated using Affymetrix Human ST 1.0 exon arrays. These data were obtained from a research study [15] at Duke University. These individuals included 55 males and 38 females, from 34 to 104 years old with an average of 74±16 years. The postmortem intervals, i.e., the time from death to brain tissue collection, were 1.2–46 hours with an average of 14.3±9.5 hours. These individuals had no defined neuropsychiatric condition. Correlations between expression of PHF3-PTP4A1 transcript and expression of other genes across transcriptome in these individuals were tested (Table S2). α was set at 3.4×10−6 ( = 0.05/14,925).
