There were a total of 114 SNPs in 79 genes that were marginally (p<10−4) associated with alcohol dependence in the AA discovery sample (data available on request). The p values from the allelewise and genotypewise association analyses of the five top-ranked SNPs before and after controlling for admixture effects are listed in Table S1. Among these top-ranked SNPs, 22 SNPs (19.3%) in 10 genes were replicable in EAs (Table S3). Among these 10 genes, only PHF3-PTP4A1 region was enriched with 12 replicable top-ranked SNPs (Table S3).