p < 0.0001) criteria than EAs, and these differences were significant even after accounting for sex and birth cohorts. The heritability of ANYDEP and drug_noalc were 0.60 (standard error (SE) = 0.043) and 0.59 (SE=0.085) respectively, in the EA families. Although the heritability of ANYDEP was lower in the AA families (0.37; SE=0.065), the heritability of drug_noalc was slightly higher (0.63; SE=0.106).