For all 13 phenotypes (12 items, sum), the SNP-based genome-wide association analyses were conducted separately on sample 1 and sample 2. To optimize the robustness of the genetic comparisons between the 13 phenotypes, we combined for all 13 phenotypes the GWA results from sample 1 and 2 using meta-analysis in METAL41. All SNP, gene, and gene-set analyses (Supplementary Data 2, 5–17, 18–30, 33–47) are thus based on the results from these meta-analyses.
