Of 7,315 gene ontology (GO) classifications 24 were associated with schizophrenia (Supplementary Table 7). All were relevant to neuronal function including development, differentiation, and synaptic transmission, and involved multiple cellular components including ion channels, synapses, and both axon and dendritic annotations. Using the expert-curated ontology of the SynGO consortium19, we further examined the synaptic signal and found that conditionally significant annotations were mainly within postsynaptic terms (Supplementary Tables 8, 9), although enrichment was also found for genes involved in synaptic organisation and signalling.
