Alcohol use in the DNS was assessed at baseline (past 12-month use) and follow-ups (questions modified to reflect use following the prior assessment) using the Alcohol Use Disorders Identification Test consumption subscale (AUDIT-C) (DNS: α = .85; mean = 3.76; SD = 2.64; range = 0–12) (32,33). The AUDIT-C was approximated (aAUDIT-C) in the HCP sample (α = .786; mean = 3.42; SD = 2.65; range = 0–12) and TAOS (α = .893; mean = 0.45; SD = 1.26; range = 0–9) using questions from Semi-Structured Assessment for the Genetics of Alcoholism (34) and Substance Use Questionnaire (35), respectively. In TAOS, the initiation of alcohol use was defined as attaining a score of ≥1 on the aAUDIT-C (i.e., participant reports consuming ≥1 full alcoholic beverage; n = 82 started during the study; age (in years): mean = 16.68, SD = 1.39, range 14.12–19.64). Supplement 1 contains additional details.
