As shown in Table 2, a significant (corrected p < .025) genotype × traumatic stress interaction on the likelihood of developing alcoholism was found for two of the block 1 SNPs: rs110402 and rs242924, These SNPs are in allelic identity (MAF = 0.461). The results of the full models for each SNP are shown in Table 5. As can be seen from Table 3A, these two SNPs appear to be driving the block 1 haplotype results. Thus the major alleles of rs110402 and rs242924, included in haplotype H1, are protective against risk of AD in individuals exposed to trauma.
