Linkage analysis of the alcohol dependence diagnosis when the temporal clustering of symptoms was not required also failed to yield any peaks that achieved genome-wide significance, but six peaks did exceed a LOD score of 1.0 (see Table 2 and Figure 1). The first peak overlapped with that described for the alcohol dependence diagnosis when the temporal clustering criterion was used (chromosome 1 at 12 cM, LOD = 1.24). The second peak was also located on chromosome 1 though closer to the centromere at 114 cM (LOD = 1.19) with a support interval that extended from 103 – 127 cM. The third peak was found on chromosome 2 at approximately 32 cM (LOD = 2.42) with a support interval that extended from 17 – 36 cM. The fourth peak overlapped with the peak on chromosome 8 described for the alcohol dependence diagnosis when the temporal clustering criterion was used (LOD = 1.11). The fifth peak was located on chromosome 9 at 18 cM (LOD = 1.70) with a support interval that extended from 6 – 27 cM, and the sixth
