Chunk #18 — Materials and Methods — Invertebrate model organism studies — Drosophila studies

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Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms.

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Only one candidate locus (RYR3) had both a Drosophila ortholog and genetic reagents available. Detailed methods for Drosophila studies are provided in Supplementary Materials and Methods.