Mill Hill Vocabulary (SAGE: P = 0.000007, β = −0.047; Yale‐Penn: P = 0.0002, β = −0.039). However, education was not significantly associated with polygenic risk, and the effect sizes were markedly reduced, after the same adjustment (SAGE: P = 0.44, β = −0.008; Yale‐Penn: P = 0.41, β = 0.008). The amount of variance in education and SIMD explained by polygenic risk for alcohol dependence was less than 0.36 percent across all models. The association between the meta‐analysis PGRS and demographic and cognitive variables is presented in Tables 1 and 2.
