Positional mapping is performed based on annotations obtained from ANNOVAR12. Two optional filters are provided to control the maximum distance from SNPs to genes and select specific functional consequences of SNPs on gene. When the former option is defined, FUMA maps SNPs to genes based on ANNOVAR annotation and a user-defined maximum distance is applied for intergenic SNPs. When the latter option is provided, FUMA maps only SNPs which have selected annotations annotated by ANNOVAR (e.g., coding or splicing SNPs).
