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Chunk #46 — Methods — Gene mapping

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Functional mapping and annotation of genetic associations with FUMA.
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For eQTL mapping, all independent significant SNPs and SNPs in LD of them are mapped to eQTLs in user-defined tissue types. By default, only significant SNP–gene pairs (false discovery rate (FDR)≤ 0.05) are used. Optionally, eQTLs can be filtered based on a user-defined P-value. eQTL mapping maps SNPs to genes up to 1 Mb apart (cis-eQTLs).