The rich longitudinal family‐based data collected by COGA over the last 30 years provides a national resource for the field. With clinical interviews, surveys, environmental information, electrophysiological phenotypes, and genotypic data collected from >17,000 individuals from multi‐generational families, COGA enables a wealth of important questions about the onset, developmental course, and consequences of AUD. The genomic data has allowed COGA to make substantive, leading contributions to gene identification for AUD and related substance use and psychiatric conditions (see 4. Genetics). Further, the longitudinal electrophysiological assessments enable study of the neural development that both precedes and follows alcohol use and problems (see 3. Brain function). Integrating these data with our lifespan clinical and environmental assessments has allowed us to characterize the pathways and mechanisms by which risk unfolds and remission takes place, and to translate these findings into personalized prevention and intervention studies (see 1. Overview). The evolving nature of the sample allows us to continually address new questions of interest to the field. As COGA participants age into mid‐ and later‐life, it provides a valuable opportunity to study the consequences
