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Chunk #13 — 3. Results — 3.2 Inhibition of eCB catabolic enzymes attenuates anxiety-like behavior in the marble burying test

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Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay.
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The highly selective FAAH inhibitor PF-3845 (10 mg/kg) significantly reduced marble burying [F(3,44) = 3.199; P < 0.05; Figure 2A], but had no effect on immobility at any dose tested (p = 0.31; Figure 2B).