Since the publication of DrugBank 5.0, there have been 919 newly approved drugs and drug salts reported across 11 different countries or regions. Of these, 393 are small molecule drugs and 526 are biotech (protein, DNA or cell-based) drugs. The biotech drugs can be further broken down into allergenics [numbering 51], gene therapies [21], cell transplant therapies [11], protein-based therapies [89] and vaccines [249]. Aside from vaccines (which are mostly protein), protein-based therapies represent the largest increase, of which 51/89 were monoclonal antibodies.
