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Chunk #58 — Cannabinoids, psychosis, and causality

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Cannabis and psychosis/schizophrenia: human studies.
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Does exposure to cannabinoids “cause” psychosis where none would have otherwise existed? The commonly applied criteria to establish disease causality include temporality, strength and direction of the association, biological gradient (dose), consistency, specificity, coherence, experimental evidence, and biologic plausibility (reviewed in [43]).