The average sibling age was 42.6 years and 54.6 years for the Australian and Finnish samples, respectively. From Australia, 289 families were selected for genome scan, which included 1309 individuals (of which 917 were offspring) who provided both genotypic and phenotypic data. From the Finnish site, 161 families were selected for genome scan, which included 541 individuals (of which 522 were offspring) with both genotypic and phenotypic data. For phenotypic analyses, we used all available data, which included 946 Australian families (3425 individuals, 2539 offspring) and 757 Finnish families (2265 individuals, 2090 offspring). Please see Saccone et al. (2007a) and Loukola et al. (2008) for further details on these samples.