Using local analysis of covariant association (LAVA), 49 univariate local genetic signals (local hg2) were examined within each trait across 2,945 partitioned semi‐independent genomic regions of ~1 Mb. Regions demonstrating univariate signals for more than one trait following Bonferroni correction (P < 2.00 × 10−5) were selected for tests of local genetic correlation (ρ g ). This resulted in 1,608 bivariate tests, with significant local genetic correlations among sensation seeking, alcohol consumption, and AUD identified by a second Bonferroni correction (P < 3.11 × 10−5).
