(top quartile vs. others; HR = 2.02; PAR = 13%). A similar effect was observed for conscientiousness (HR = 0.69; 95%CI =0.55–0.87), and as illustrated in Figure 1, the risk of incident AD was threefold higher for the group in the lowest compared to the highest quartile of conscientiousness (HR = 3.26; 95%CI = 1.43–7.40; absolute risk 8% and 2% for the lowest and highest quartiles). Similar to neuroticism, the proportion of AD cases that could be attributed to low conscientiousness (bottom quartile vs. others; HR = 1.74) was about 10% (PAR = 11%).
