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Chunk #21 — Discussion

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EEG microstate analysis in drug-naive patients with panic disorder.
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In the present study, we also demonstrated fewer occurrences in microstates of class C in patients with PD. In a previous study, class C was a predominant microstate class in healthy adult subjects recorded during eyes closed relaxation [29], associating class C with a relaxed idling state. The increased arousal patients may thus reduce the occurrence of microstates of class C. In another study by Mueller et al (2005), the occurrence of microstates of class C were associated with the break-down of a top-down driven illusionary motion, and their occurrence was reduced during periods when a new percept was constructed [52]. One may therefore speculate that the reduction of the number of microstates of class C relates to a difficulty of the patients to re-consider a previously made cognitive-emotional evaluation of some environmental stimuli.