To address fulfillment of the CARR responsibilities in the biobank research system of which the biobank is a part, the biobank should have a multidisciplinary committee such as an Incidental Findings Committee, Return of Results Committee, or Informed Cohort Oversight Board. These committees, focusing on IFs and IRRs issues, will need to interact with other relevant committees, particularly the IRBs at the biobank and at the primary research or collection sites.