Of the sample, 16.0% (SE=0.3) experienced childhood or adolescent parental divorce/separation, 21.3% (SE=0.4) reported a parental history of alcohol problems, and 6.0% (SE=0.2) experienced both parental divorce/separation and parental history of alcohol problems. The age of offspring at the time of parental divorce/separation ranged from 1 to 17 years, with the average age being 9 years and most frequent age being 5 years. Of those reporting childhood or adolescent parental divorce/separation, 18.8% (SE=0.7) met criteria for DSM-IV lifetime alcohol dependence compared to 11.3% (SE=0.4) who did not experience childhood or adolescent parental divorce/separation. Of those with parental history of alcohol problems, 23.1% (SE=0.6) met criteria for DSM-IV lifetime alcohol dependence compared to 9.6% (SE=0.3) who did not experience parental history of alcohol problems. Of those reporting both parental divorce/separation and parental history of alcohol problems, 26.1% (SE=1.1) met criteria for DSM-IV lifetime alcohol dependence.