With these rich, cross‐sectional and longitudinal data, collected within families over decades, a number of critical questions about the causes, consequences, and life course of alcohol use problems and related disorders have been addressed, and more can be studied. Below we provide illustrative examples of areas where COGA data has made substantive contributions to a deeper understanding of the AUD phenotype, its comorbidity with other addictions and with psychiatric disorders, and of the impact of the interplay of genetic and environmental influences on alcohol and other substance use outcomes. We note that COGA data and instruments are made available to any qualified investigator and can be accessed through a variety of routes, including directly from NIAAA, through direct collaboration with COGA investigators, and through dbGAP; details about each of these options are provided at https://cogastudy.org/resources-for-researchers/ with additional details in the companion paper 1. Overview. We welcome collaborations with outside investigators; indeed, some of COGA's most impactful papers have arisen through collaborations with the global community of researchers, such as the Psychiatric Genomics Consortium, 15 , 16 , 17 , 18
