All PGSs were robustly associated with higher mean levels of CON and HED when these were averaged across time (Table 1). The only exception was BeerPref PGSs, which were associated with a higher level of HED (meta β=0.064, p=3.65E-05) but not CON. Consumption PGSs were the strongest predictor of mean CON (meta β=0.333) while Problems and EXT PGSs were the strongest predictors of mean HED (meta β=0.154–0.178). In FTC (Table 2), Problems, Consumption, and EXT PGSs were significantly associated with higher mean Freq (β=0.215–0.317) while Problems, BeerPref, and EXT PGSs were all associated with higher mean levels of gEtOH, Heavy drinking, and PassOut frequency (β=0.025–0.155). Across all analyses, the within-sample variance in AUBs accounted for by each PGS was less than 2%.
