NCBI's prokaryotic (see below) and eukaryotic annotation pipelines have kept pace with the increasing number of genome assemblies submitted to INSDC by providing consistent annotation onto RefSeq copies of selected high quality submitted genome assemblies. To date, 245 eukaryotic genomes, including 170 vertebrate genomes, have been annotated by this pipeline, of which more than 120 species were annotated in the past 20 years. Among this group are 52 bird species that include representative species of most avian orders (9,10). There has also been a significant expansion in the number of RefSeq-annotated assemblies for non-human primates, other mammals, fish, plants, and arthropods.
