infused bilaterally into the hippocampus. Subsequent studies evaluated whether intrahippocampal administration of the active rimonabant dose would block the memory disruptive effects of systemically administered cannabinoids. To control for the possibility that rimonabant elicited its effects because of diffusion to distal areas, we also evaluated whether rimonabant infused outside the borders of the hippocampus would block memory deficits caused by systemic cannabinoid administration.
