Chunk #25 — RESULTS — Multivariate GWAS confirm a distinct genetic basis between alcohol consumption and misuse

Source

Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts.

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Some loci included genes that were only associated with Consumption (Table S31), such as KLB, RCF1 and the MAPT/CRHR1 region, which were previously associated with alcohol consumption behaviors (3–5, 33), and other novel candidate genes for alcohol, such as CPS1, previously associated with metabolic conditions (Table S13).