Kayser and colleagues have implemented CSD methods in a series of studies on schizophrenic patients in a variety of task conditions based on a rationale (for each study as mentioned below) derived from the findings of the schizophrenia literature. In order to unravel the subprocesses of verbal working memory deficits in schizophrenia, Kayser et al. (2006) used the CSD method in a visual word serial position task and found that schizophrenic patients showed reduced left inferior parieto-temporal P3 sources. Using tonal and phonetic oddball tasks, Kayser et al. (2010a) studied ERP generator patterns as elicited by temporal PCA to examine the earlier findings showing left-lateralized dysfunction in schizophrenics with greater left than right reductions of P3 amplitude, and found a bilateral reduction in fronto-central N2 sinks and parietal P3 sources. In another study, using visual continuous recognition memory tasks with common words or unknown faces, Kayser et al. (2010b) investigated whether the visual recognition memory deficits in schizophrenics were restricted to only words. This study involved the episodic memory effect, also known as ‘old/new’ effect, as indexed by an early
