Table I shows the number of affected sibling pairs, LOD scores, and allele sharing for each of the phenotypes using the primary COGA microsatellite linkage panel and the SNP linkage panel available on a subset of the full COGA sample. Since LOD scores are influenced by sample size, and different numbers of sibling pairs were available for each of the phenotypes (and between the microsatellite and SNP linkage panels), allele sharing is provided in Table I to allow comparisons across the phenotypes and across the two sets of linkage analyses. Although the LOD scores differ across the micro-satellite and SNP linkage panels (not surprising due to differences in sample sizes and methodology), the pattern of allele sharing observed using the microsatellite and SNP linkage panels is largely consistent. Of the individual phenotypes, CD and SUI yield higher rates of allele sharing than AD. The allele sharing for AD with CD or SUI was considerably elevated compared to the full AD analysis, and the AD or CD or SUI showed only a very small elevation in allele sharing. Further, the combined
